Thursday, July 4, 2013

Bid cities, presidential contenders to make case

With the voting just over two months away, the bidding for the 2020 Olympics and the race for the IOC presidency are reaching a pivotal stage.

Both campaigns come together this week in Lausanne as the three bid cities and six presidential candidates make vital presentations to the voters ? the 100-plus members of the International Olympic Committee.

Istanbul, Madrid and Tokyo make their pitches to the IOC assembly on Wednesday, with the Turkish city having the most at stake following the wave of anti-government protests that swept the country. The presidential contenders present their platforms to the members on Thursday.

Both events could prove decisive going into the final weeks before the IOC session in Buenos Aires, Argentina, where the members will vote by secret ballot for the host city on Sept. 7 and the new president on Sept. 10.

The presentations will be made behind closed doors at the Beaulieu convention center. The bid cities will each have 45 minutes to make their case, with another 45 minutes allotted for questions and answers. The presidential candidates will each have 15 minutes to outline their manifestos.

Overseeing the proceedings will be IOC President Jacques Rogge, who steps down in September after 12 years in office. He served an initial eight-year term and was elected to a second four-year mandate.

Vying to succeed Rogge are: IOC vice presidents Thomas Bach of Germany and Ng Ser Miang of Singapore, executive board members Sergei Bubka of Ukraine and C.K. Wu of Taiwan, and former board members Richard Carrion of Puerto Rico and Denis Oswald of Switzerland.

The presidential race is generating more buzz than the 2020 contest among the members.

"Basically the most important thing we do is to elect a president," senior Norwegian IOC member Gerhard Heiberg told The Associated Press. "It's more important than organizing cities for the games. We have many challenges coming.

"We will elect a person for eight years. This person will mean a lot of difference in the IOC, the thinking, the strategy. I meet a lot of IOC members and they talk about nothing else."

Bach has been considered a front-runner, but favorites don't always win in the unpredictable world of IOC elections.

All six candidates have already sent their campaign platforms to the members. Now the voters will get a chance to see and hear them in person, the first time such presentations have been organized for an IOC presidential campaign.

The six will speak one after the other. It is not a debate and no questions will be allowed. The IOC says it wants to keep the format to a controlled, civil campaign.

"They have 15 minutes to stand in front of the session, to show their personality and to lay out their programs for the eight years coming," Heiberg said. "This will give a good indication, especially for members who don't know the six, to finally get to see them performing."

The candidates' platforms have steered away from revolutionary change and centered on common themes: reaching out to youth, stepping up the fight against doping, reviewing the bidding process for the games, improving the system for selecting sports on the Olympic program, raising the 70-year age limit for IOC members.

"The race really starts this week," Heiberg said.

By contrast, the 2020 bid cities have been campaigning for nearly two years already, but this will be the first time they appear before the IOC assembly. All three are bringing high-ranking delegations to try to earn the members' trust and confidence.

"The ones who don't take this seriously make a big mistake," Heiberg said.

It was at a similar meeting in 2009 that Rio de Janeiro seized the momentum in the race for the 2016 Games, focusing on the theme that the Olympics had never been to South America and Brazil was an emerging economic force.

Last week, the IOC released a technical evaluation report on the 2020 bid cities to give members as much factual information as possible. The report did not rank or grade the cities, but Tokyo appeared to come out the best overall.

Istanbul is bidding for a fifth time, Madrid is back for a third consecutive time and Tokyo is trying for a second time in a row.

Istanbul is inviting the IOC to take the Olympics to a new region, to a predominantly Muslim country for the first time, to a city that connects Asia and Europe. Tokyo claims to be a "safe pair of hands" at a time of global economic and political uncertainty. Madrid, despite Spain's severe financial troubles, boasts that it would spend far less money than the others on infrastructure because 80 percent of its venues are already in place.

No city has more at stake than Istanbul, following the unprecedented street demonstrations across the country in June. Prime Minister Recep Tayypip Erdogan, facing the biggest challenge to his 10-year rule, has come under international criticism for his crackdown on the protests. Turkey's image has also been hit by a spate of doping cases in recent weeks.

"Although the games will be seven years ahead, what's going on (in Turkey) right now is important to the voting of the members," Heiberg said. "There will be many questions, absolutely. This is a good opportunity for Turkey, for Istanbul, to answer the questions and lay it out in the open how they think, what they're going to do about it."

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/347875155d53465d95cec892aeb06419/Article_2013-07-02-OLY-IOC-Meetings/id-9861195dea4f479aa1c2a352e130b928

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Wednesday, July 3, 2013

Obama ends Africa trip by joining Bush at memorial

President Barack Obama toasts with Tanzanian first lady Salma Kikwete during an official dinner at the State House in Dar Es Salaam, Tanzania, Monday, July 1, 2013. The president is traveling in Tanzania on the final leg of his three-country tour in Africa. (AP Photo/Evan Vucci)

President Barack Obama toasts with Tanzanian first lady Salma Kikwete during an official dinner at the State House in Dar Es Salaam, Tanzania, Monday, July 1, 2013. The president is traveling in Tanzania on the final leg of his three-country tour in Africa. (AP Photo/Evan Vucci)

President Barack Obama, followed by first lady Michelle Obama, does a dance upon his arrival ceremony with Tanzanian President Jakaya Kikwete, right, Monday, July 1, 2013, at Julius Nyerere International Airport in Dar Es Salaam, Tanzania. The president is traveling in Tanzania on the final leg of his three-country tour in Africa. (AP Photo/Evan Vucci)

(AP) ? Democratic President Barack Obama and former President George W. Bush are proving that it's a small world after all, with an extraordinary chance encounter a long way from home.

Obama and his Republican predecessor plan to appear together briefly Tuesday, when by coincidence both will be in the same city on Africa's east coast promoting development on the continent. Obama is on the final day of a weeklong tour of the continent, while the George W. Bush Institute is hosting a two-day summit on African women.

Initially the two men had no plans to meet, but the White House announced Monday that they would gather at a memorial for Americans killed in the U.S. Embassy bombing here nearly 15 years ago. They plan to lay a wreath in honor of the 11 Americans who died in the attack masterminded by Osama bin Laden, along with a near-simultaneous bombing at the U.S. Embassy in neighboring Kenya.

Meanwhile, first lady Michelle Obama and Laura Bush planned to appear together on a panel at the conference on empowering African women. President Bush plans to deliver his own speech there Wednesday, after the Obamas have returned to Washington.

Obama has credited Bush with helping save millions of lives by funding AIDS treatment. "I'm looking forward to being able, on African soil, to once again thank him on behalf of the American people for showing how American generosity and foresight could end up making a real difference in people's lives," Obama said Monday.

But Obama also said he wants to change the approach the U.S. takes with Africa. "We are looking at a new model that's based not just on aid and assistance, but on trade and partnership," he said.

"Ultimately, the goal here is for Africa to build Africa for Africans," Obama said. "And our job is to be a partner in that process."

In that spirit, Obama has announced a new trade agreement with eastern African nations and a program to bring more power to Africans who don't have access to electricity. His final event Tuesday is a speech at Tanzania's Ubungo Power Plant, which was funded by a U.S. grant and built by American corporations Symbion and General Electric.

"There's enormous potential here in Tanzania to start getting electricity out into villages in rural areas, more reliable service that can then power manufacturing, power new businesses which creates more jobs, creates more demand," Obama explained.

___

Follow Nedra Pickler on Twitter at http://www.twitter.com/nedrapickler

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/3d281c11a96b4ad082fe88aa0db04305/Article_2013-07-02-Obama/id-019a25fe9b724a088943919dcedf4f71

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Friday, June 28, 2013

Try These Great Tips For Your Home Improvement Project ...

Home improvement is likely an engaging topic for nearly every homeowner. Everyone wants their home to look great; however, undertaking a large improvement project can be overwhelming. Read this article to learn what you need to know about the basics of home improvement.

Changing air filters is paramount. This will bring in healthier air and keep your air conditioners and heaters running efficiently. Many service calls are placed each year because of dirty filters.

If you are running out of counter space in your kitchen, consider an over-the-range microwave. You can find these type of microwave ovens in a variety of prices. Many of them have special features like convection cooking. A lot of units use a filter and not a vent; these are meant for those who do not need a lot of ventilation.

It is important that you focus your improvement work on the visible portions of your home. Potential buyers base their judgment on things they see, and having unsightly things such as cracked and peeling paint or a yard overgrown with weeds can be a cause for them to walk from a good deal. It is very true that a lot of home improvments cannot be seen but you need to take care of the ones that can be seen first.

In many home improvement projects, using ?premium? materials is a way to maximize the value of the work. Comparison shop for these building supplies before choosing a vendor! It can cost a lot of money to install a new floor, so be sure to shop around to find the best deals. There are supply stores that give out discount and you could also look for bargain places that could help you.

As you read in the beginning of this article, improving your home is not as scary as it may seem. The skills you learn in one renovation project make future projects much easier to take on. Follow our tips to be ready for the next home improvement project that presents itself.

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This entry was posted in Swimming Pool Orlando and tagged improvement project, orlando pool builders, orlando pools, pool builders orlando, pools orlando by admin. Bookmark the permalink.

Source: http://www.poolbuildersinorlando.com/try-these-great-tips-for-your-home-improvement-project/

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Tuesday, June 11, 2013

Obama to nominate Furman as top economic adviser

President Barack Obama talks to family members standing on the Truman balcony of the White House as he walks from Marine One on the South Lawn after returning to Washington, Sunday, June 9, 2013. Obama spent the weekend in California where he met with Chinese leader Xi Jinping. (AP Photo/Susan Walsh)

President Barack Obama talks to family members standing on the Truman balcony of the White House as he walks from Marine One on the South Lawn after returning to Washington, Sunday, June 9, 2013. Obama spent the weekend in California where he met with Chinese leader Xi Jinping. (AP Photo/Susan Walsh)

(AP) ? President Barack Obama will nominate Jason Furman, a veteran White House economic official, as chairman of the president's Council of Economic Advisers.

The White House says Obama will make the announcement Monday afternoon.

The council is one of two of the president's main sources of economic advice to the president. The other is the National Economic Council, where Furman currently serves as principal deputy director.

If confirmed by the Senate, Furman would replace Alan Krueger, who is returning to his former post as a professor at Princeton University.

Furman's research has been focused on fiscal and tax policy, Social Security and monetary policy. Furman, 42, worked as an economist in the Clinton White House and before that was a senior adviser at the World Bank.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/89ae8247abe8493fae24405546e9a1aa/Article_2013-06-10-Obama-Economist/id-ef0618d5a1cd49619ed26616822a549c

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Jury selection begins in George Zimmerman trial

George Zimmerman, accused in the Trayvon Martin shooting, in Seminole Circuit Court during his pretrial hearing??

Lawyers on both sides of the George Zimmerman trial Monday began what is expected to be a weekslong process of selecting a 12-member jury in the incendiary case in Sanford, Florida.

As potential jurors filled out questionnaires, Judge Debra Nelson denied a request from Zimmerman's attorneys to delay the start of the trial for several weeks on grounds they needed more time to prepare.

His attorneys declined to ask for a change of venue in the case, suggesting they are confident they can find impartial jurors in the area despite the wall-to-wall media coverage that 17-year-old Trayvon Martin's killing attracted last year.

But his brother, Robert Zimmerman, didn't sound convinced. "We're obviously concerned about that," he told reporters Monday when asked if he believed George Zimmerman could get a fair trial.

Zimmerman, out on $1 million bond and in hiding for much of the past year, is charged with second-degree murder for killing the unarmed teen in a confrontation in his gated community, where Zimmerman acted as a volunteer watchman.

Prosecutors argue that Zimmerman racially profiled, followed and then shot Martin. Zimmerman's lawyers counter that their client was attacked by Martin and that he acted in self-defense.

Defense lawyer Jose Baez, who represented Casey Anthony in her high-profile trial in Orlando in 2011, said jury selection in this trial will be especially complicated because of the case's racial overtones. (Zimmerman identifies himself as Hispanic; Martin was black.)

Martin's family hinted at the potential complications in a statement released Monday morning.

"Trayvon's life was taken unnecessarily and tragically, but we call upon the community to be peaceful. We have placed our faith in the justice system and ask that the community do the same," the family wrote.

Generally, defense lawyers would be more likely than prosecutors to want to select minorities for a jury, since, on average, African-American and Hispanic people express more skepticism of law enforcement than white people, according to Baez. But in this case, Zimmerman's defense lawyers will want to pack the jury with white "gun-toting Republicans" who would be amenable to their argument that their client shot and killed the unarmed Martin in self-defense, Baez said.

These jurors might also be more convinced by the argument that local police made the right decision not to arrest or charge Zimmerman in the shooting initially.

"It's a very unique case in that respect, where the general rules that a lot of lawyers use are just going be absolutely flipped upside down," Baez said. "Because it is such a racially charged case, I think that the clear line is going to be drawn here between African-American jurors and Caucasian and Hispanic jurors."

But the defense team will have to be very careful in its quest to find conservative jurors more amenable to the self-defense argument. Circuit Judge Debra Nelson, who is presiding over the televised trial in the Seminole County Courthouse, will most likely be vigilant to make sure neither side is excluding jurors based on their race, which is illegal under a 1985 Supreme Court decision.

"I think this judge is fully aware of the racial tensions involved and is going to be on high alert," Baez said. If the defense team moves to dismiss an African-American juror during the peremptory strike phase of jury selection, for example, the judge could challenge it to provide a reason for the move. If the team can't come up with a good reason (for example, that the juror attended a rally in support of Trayvon Martin), the judge will assume the attorneys wanted to dismiss the juror for racial reasons and override their preference.

Nelson has ruled that the pool of 500 potential jurors will be kept anonymous during the selection process. It's possible she could order them sequestered during the trial, which is what happened to the jurors in the Anthony case. Nelson rejected the defense's request to sequester them during jury selection.

The pool will shrink rapidly as jurors can make the case that sitting on a jury for weeks would be a hardship. After that process winnows down the lot, the attorneys will go through and disqualify anyone with a personal connection to the case. Both sides will be on the lookout for jurors who have stated their support for either Zimmerman or Martin on social media sites, or been involved in activism around the case. The attorneys may also have potential jurors fill out questionnaires gauging their beliefs about gun control, law enforcement, race and other issues.

Yahoo's Jason Sickles contributed reporting.

Source: http://news.yahoo.com/blogs/lookout/jury-selection-begins-george-zimmerman-trial-121304344.html

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Interferon-beta aids balance and movement in mice with spinocerebellar ataxia 7; first in vivo study of the treatment for this condition shows significant physical improvement

June 9, 2013 ? The first in vivo trial of the use of interferon-beta in a mouse model of the group of fatal diseases known as spinocerebellar ataxia has shown that its use can significantly improve their physical condition and control symptoms. Researchers in France and the US believe that their results show that a clinical trial in humans is merited.

The group of genetic conditions known as spinocerebellar ataxias currently have no treatment or cure and are always fatal, in the case of affected children at an early age. Symptoms include a progressive lack of co-ordination of gait, and poor co-ordination of hands, speech and eye movements, due to a failure of co-ordination of muscle movements. Now researchers from France and the US have found a new way of controlling the symptoms and significantly improving the physical condition of animal models of the disease, the annual conference of the European Society of Human Genetics will hear today (Monday June 10).

Dr. Annie Sittler, from the Centre National de la Recherche Scientifique (CNRS), working in the team of Professor Alexis Brice at the research centre Brain and Spinal Cord Institute (CR-ICM), Paris, France described the team's work in the field of polyglutamine disease, a group of neurodegenerative conditions involving abnormal protein conformation. "Accumulation of a polyglutamine-containing protein known as mutant ataxin -7 is responsible for neurotoxicity, neuronal dysfunction, and eventually neuronal death," she explains. "We had previously shown in cells that mutant ataxin-7 was degraded in nuclear bodies, structures found in the nucleus of cells, by a protein known as promyeloctyic leukemia protein or PML, and that interferon-beta could help with this process and protect against disease."

The researchers used a mouse model of a particular form of spinocerebellar ataxia known as SCA7. The genetically-modified 'knock-in' mice develop the severe type of the disease, similar to the infantile human version, and have a very short lifespan of around 14 weeks. They were injected with mouse interferon-beta three times a week, starting at five weeks of age, just before their first symptoms of disease were due to appear. Investigation of their brains post-mortem showed that the mice who had received the interferon-beta, as opposed to those in the control group, had a reduced load of mutant ataxin-7.

On the physical level, substantial improvements in the interferon-beta treated mice were noticed. "At twelve weeks of age the physical performance of the mice that received the active substance was significantly improved compared to the control group. We gave them a locotronic test, where they have to cross a kind of ladder. This test is used to check motor co-ordination when walking. We also put them through a beam-walking test, which enables us to measure their balance and limb co-ordination. The treated mice did much better in both of these tests," Dr. Sittler will say.

Further proof of the positive effects of interferon-beta came from analysis of the PML nuclear bodies, involved in many cellular processes such as transcriptional regulation and apoptosis. A subset of these nuclear bodies is responsible for regulating the degradation of accumulated misfolded proteins in the cell nucleus. The treated mice had more, and very much larger, PML bodies, and they were present in the Purkinje cells, responsible for motor co-ordination emanating from the cerebellum The researchers further found that these PML bodies were clastosomes, the specialised nuclear bodies involved in the degradation of mutant ataxin-7 and other polyglutamine-containing proteins. "This, together with the physical improvements we saw in the interferon-beta treated mice, was the proof we needed that our findings in the cell could be successfully transferred to living animals," says Dr. Sittler.

"Now that we have found that interferon-beta can slow progression of disease in SCA7 mice, we believe that, after confirmation in another mouse model, it would be merited to test its effects on humans in a clinical trial,," she will say. "Such trials are difficult in rare diseases, since a special design is needed to test a hypothesis on a small number of patients. However, there are a number of other polyglutamine diseases, for example Huntington's, where patient numbers are larger, and the effects of the condition just as devastating. We hope that our results will encourage others to collaborate with us in order that we may be able to pursue our research to the benefit of all those afflicted with spinocerebellar disorders."

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_health/~3/SHfKGHW_WWg/130609195625.htm

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Friday, June 7, 2013

World's Oldest Tumor Found In a Neanderthal Bone

First time accepted submitter minty3 writes "A fibrous dysplasia tumor has been found in the bone of a Neanderthal that is more than 120,000 years old. The world's oldest tumor in a Neanderthal rib was part of a collection of bones, which were excavated more than 100 years ago from a site in Krapina, Croatia. They were X-rayed in the 1980s, and initially didn't reveal the tumor. It was only when scientists took a closer look at a radiograph where a rib fragment appeared to be 'burned out' did they return to the rib and subject it to higher quality scans."

Source: http://rss.slashdot.org/~r/Slashdot/slashdotScience/~3/YaRtxl98Vzo/story01.htm

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